>zebrafish MAALRVVVFSGTGRTLLNTSKAFHTPRASMSFASLPKGKKIALTTIGVLTTGGAGLALMLQQSVKASDLE LHPPTYPWSHGGFLSSLDHASVRRGYQVYKQVCSACHSMEYLAFRNLVGVSHTEDEVKTLAEEIEVVDGP DDNGEMFTRPGKLSDYFPKPYANPEAARAANNGALPPDLSYIVNARHGGEDYVFSLLTGYCDPPAGVSLR EGLYYNPYFPGQAIGMAPPIYNEVLEYDDGTPATMSQVAKDVCTFLRWAAEPEHDDRKRMGLKVLLGGAL LIPLIYYIKRHKWSVLKSRKIAYRPPK >dendrogramma MANPVKRKLLNTAVNCYSLFSTSSAQAAKRSSLRWAAAGVLTAGGLGVGYTLHQAVNAEDYNLHPPHFEWNHKGNLQSLDHASIRRGYLVYKQVCASCHSMEQIAYSNLVGISHTEEEAKALAEEVQVTDGPDEEGNMFQRPGKLSDYFPDPYPNEEAARAANNGAFPPDLSLITSASHGGEDYMFAILTGYMEEPPAGIELREGMSYNVYFAGQAISMAQQLYYGVMDYDDGTPATVSQMSKDISIFLKWAAEPEHDESKRMGLKVLSILVTMAGIALYYKRHKWSVLKSRKLIYRSTSV* >human MAAAAASLRGVVLGPRGAGLPGARARGLLCSARPGQLPLRTPQAVALSSKSGLSRGRKVMLSALGMLAAG GAGLAMALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCASCHSMDFVAYRHLVGVCY TEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPNSEAARAANNGALPPDLSYIVRARHGGEDY VFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDGTPATMSQIAKDVCTFLRWASEP EHDHRKRMGLKMLMMMALLVPLVYTIKRHKWSVLKSRKLAYRPPK >sea_urchin MAAILRKTSGLLRVNSGILCPKAKLSGFAHMSRTKKAALVTFGALAAGSTGLVSALHISVSAEEYDIHPP NLIWPHSGVFSTFDHASLRRGYQVYKEVCSACHSMQYLAFRNLVGVTHTEAEAKTIAEEFQIPDGPDEEG EMFERPGKLSDYFPKPYANDEAARAANQGALPPDMSYIALARHGNENYIFALLTGYCEPPAGVEVKGDLY YNPYFPGQAIGMAPPIYNEIIEYEDGTPATMGQIAKDVSTFLRWASEPEHDERKRMGLKALMVLSMILGV AYYTKRHKWSVLKSRKLAYRPPTA >amphioxus MIRVSCFIPSQANMSSFSKMSTGKKVLFGTLGAVTAGGAGLLGALHYSTTVHAGELELHPPKFPWSHNGL FNALDHASIRRGYQVYKEVCAACHSMQYLAFRNLVGVSHTEEEAKALAEEIEVLDGPDEEGEMFMRPGKL SDYFPRPYANEEAARAANNGAYPPDLSYIILARHGGEDYVFSLLTGYCDAPAGKELRDGQYYNPYFPGQA ISMAQALYNEIIEYEDGTPATQSQLAKDVCTFLRWASEPEHDQRKRMGLKALMIASMVIAFFYYLKRHKW SVLKSRKIAYRPPQ >ciona MSLNLYKQATPKLLSMRHLQTQRKRSLSTFIKRNGKLLCGTTAVVVGAACATGFLLHQCAKASDDELHTP HYPWQHRPILKTLDAASVRRGYEVYRQVCAACHSMEYLAFRNLVGVSHTEEEAKALAAQAQILDGPNELG KMFKRPGRLSDYFPKPYANDDEARAANNGALPPDLSFIVLGRHGEEDYIYSLLTGYYDPPAGVTIGEDQH YNAYFPGQAIGMAQALYNEIIEYEDGTPAVQSQLAKDVSTFLRWAAEPHHDTRKLSGFRVACFGLLFLPL FWFQKKRIFSLVKSKKIAFKG >oyster MATVGNRVARQAFLKAKTVQNSTQANFGSFNNSPKGFKMLGLIAGTTAVVGGIGTYIAVKGAVNASTELM LHPPKYPWWHRGWFTEIDKKSARRGYMVYKQVCSACHSLNRVRFREMIGIIFTEEEAKAEAAEYQIIDGY DENNMPIKRPGKLFDAIPSPYDNQIQAENANNGVAPPDLSYVVLGREGGEDYIFSLLTGYHEPPAGVKLP EGVHYNPYFPGGLIAMAQALYDEIIEYEDGTPATQSQLAKDVTTFLTWAGEPYYDSKKALEFKAYILLGM LFAGSYYFYRRTWSSLKHKLVVPNYSKPKKDVLRAKRPGKPKGAPRS >drosophila MAATLRRFHGLRLLKSAPALSLQQAKNLSSAGSWASGNKKLIGALGAITGGVGALIYALEQSVQASGGEV HSPAQLWNHKGLFDALDHQSVRRGYEVYKQVCSACHSMQYIAYRNLVGVTHTEAEAKAEAEQITVKDGPD DTGNYYTRPGKLSDYFPSPYPNEEAARAANNGAYPPDLSYIVSARKGGEDYIFSLLTGYHDAPAGVVLRE GQYFNPYFPGGAISMAQVLYNEVIEYEDGTPPTQSQLAKDVATFLKWTSEPEHDDRKQLLIKVIGILGFL TVISYYIKRHKWSSLKSRKIVFVPKEK >hydra MFGHIKFSDLSRLGKAVVQVSKLSTSSKASKYFSLSWLSASALATSALGLGYTLYQLPLGAEALSLHPPK HRWSHSGLLDSLDHASIRRGYQVYKQVCVACHSMDQIAFRNLVGVSHTEEEVIELASQVQVTDGPNEKGD MFLRPGKLFDYFPKPYRNEEEARAANNGAYPPDLSWIVPARHGCEDYIFALLTGYREEPPAGVKLQEGMS YNVYFPGQAIAMPQQLYPGVMEYDDGTPATVSQMAKDVSTFLKWASEPEHDTKKRMGMKALVICGAMILI SLYVKRHKWSVLKSRKLVYHSPAR >sponge MATGAQVVFRRLCKLYSSSSTKGTTASFKMSSRYFGTLAAAAFGSGVVLTSLVASDDAVHPPKYPWDHKG VFSALDHRSIRRGYQVYKEVCSACHSMQYVAFRHLVGVSHTEEEARALAEEYEYPGDIDEEGNPTTRQGK LSDYFPNPYPNEEAARAANNGALPPDLTLIVLARHGEEDYIFSLLTGYYDPPAGVEVREGLAYNPYFPGG AIGMPQQLYDGGIEYEDGTPATVSQMAKDVTTFLRWSADPKHDERKRMGMKGVIILSLLVGITLYWKRQK WSLLKSRKILYYERP >yeast MFSNLSKRWAQRTLSKSFYSTATGAASKSGKLTQKLVTAGVAAAGITASTLLYADSLTAEAMTAAEHGLH APAYAWSHNGPFETFDHASIRRGYQVYREVCAACHSLDRVAWRTLVGVSHTNEEVRNMAEEFEYDDEPDE QGNPKKRPGKLSDYIPGPYPNEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAGVALPP GSNYNPYFPGGSIAMARVLYDDMVEYEDGTPATTSQMAKDVTTFLNWCAEPEHDERKRLGLKTVIILSSL YLLSIWVKKFKWAGIKNRKFVFNPPKPRK